KARL FISCHER REAGENT Chemical compatibility with O-rings, rubbers, & plastics
Karl Fischer reagent is a chemical solution used to determine water content in various substances through the Karl Fischer titration method. It typically contains iodine, sulfur dioxide, a base (such as pyridine), and a solvent (such as methanol). This reagent is widely used in laboratories for precise moisture analysis in pharmaceuticals, food, chemicals, and other industries. Despite its accuracy, Karl Fischer reagent can be hazardous. It is corrosive and can cause skin and eye irritation, as well as respiratory issues if inhaled. Proper handling, storage, and safety measures, including the use of personal protective equipment, are essential to ensure safe usage and accurate results.
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