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KARL FISCHER REAGENT Chemical compatibility with O-rings, rubbers, & plastics

Karl Fischer reagent is a chemical solution used to determine water content in various substances through the Karl Fischer titration method. It typically contains iodine, sulfur dioxide, a base (such as pyridine), and a solvent (such as methanol). This reagent is widely used in laboratories for precise moisture analysis in pharmaceuticals, food, chemicals, and other industries. Despite its accuracy, Karl Fischer reagent can be hazardous. It is corrosive and can cause skin and eye irritation, as well as respiratory issues if inhaled. Proper handling, storage, and safety measures, including the use of personal protective equipment, are essential to ensure safe usage and accurate results.

Need KARL FISCHER REAGENT resistant plastics, O-rings, rubbers, and seals? Get in touch now!


Canyon Components strives to meet all customer service requests. If you need something that isn't listed below, feel free to contact a Canyon Components product and application consultant and let our knowledgeable staff help you design the perfect part for your needs.

Paint covered o-ring
MaterialPerformanceGet a quote
FFKM (CanRez™, Kalrez®, Chemraz®)--- Insufficient Testing DataGet a quote
FKM ETP (Viton® Extreme)--- Insufficient Testing DataGet a quote
FKM (Viton®)--- Insufficient Testing DataGet a quote
NBR (Buna-N, Nitrile)--- Insufficient Testing DataGet a quote
HNBR (Hydrogenated Nitrile)--- Insufficient Testing DataGet a quote
EPDM (Ethylene Propylene)--- Insufficient Testing DataGet a quote
Aflas® (TFE/P, FEPM)--- Insufficient Testing DataGet a quote
Silicone (VMQ, PVMQ)--- Insufficient Testing DataGet a quote
Fluorosilicone (FVMQ)--- Insufficient Testing DataGet a quote
Polyurethane (PU, AU)--- Insufficient Testing DataGet a quote
Teflon® (PTFE)--- Insufficient Testing DataGet a quote
Neoprene (Chloroprene)--- Insufficient Testing DataGet a quote
SBR (Styrene-Butadiene)--- Insufficient Testing DataGet a quote
ACM (Acrylic Rubber)--- Insufficient Testing DataGet a quote
Butyl (IIR, Isobutylene Isoprene)--- Insufficient Testing DataGet a quote
Butadiene Rubber (BR)--- Insufficient Testing DataGet a quote
Isoprene Rubber (Polyisoprene)--- Insufficient Testing DataGet a quote
Natural Rubber (NR)--- Insufficient Testing DataGet a quote
Hypalon (CSPE)--- Insufficient Testing DataGet a quote
Metal Piston

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